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KMID : 1007520150240010341
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Food Science and Biotechnology
2015 Volume.24 No. 1 p.341 ~ p.345
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Effect of UV Irradiation on the Antioxidant and Anti-adipogenic Activities of Quercetin
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Heo Da-Jeong
Shon Myung-Soo
Kim Gyo-Nam
Lee Seung-Cheol
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Abstract
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Quercetin is one of the most abundant flavonol in the human diet and it is found in various plants. Although many of the biological activities of quercetin have been well described, the effect of UV irradiation on its physiological function is still relatively unknown. In this study, we compared the antioxidant and anti-adipogenic activities of intact and UV-irradiated quercetins. The UV irradiation significantly and markedly attenuated the antioxidant activity of quercetins, as determined by the DPPH radical scavenging assay. However, the UV irradiation had little effect on its anti-adipogenic activity, which was determined using 3T3-L1 adipocyte differentiation model. Taken together, these results suggest that the antioxidant and anti-adipogenic activities of quercetin are independently modulated through molecular and chemical based mechanisms.
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KEYWORD
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quercetin, UV irradiation, antioxidant, antiadipogenic
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